All About Albumin

Author: Theodore Peters, Jr.
Publisher: Academic Press
ISBN: 0080527043
Format: PDF, ePub, Mobi
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The first of its kind, All About Albumin summarizes the chemistry, genetics, metabolism, clinical implications, and commercial aspects of albumin. It provides the most up-to-date sequences, structures, and compositions of many species, and includes more than 2000 references. Key Features * Includes up-to-date sequences, structures, and compositions of many species * Reviews the protein chemistry, genetic control, and metabolism of albumin * Covers medical and cell culture applications in vivo and in vitro, with a section on handling albumin in the laboratory * Presents the relationship of albumin to its superfamily with an updated scheme for their evolution * First complete coverage of all aspects of serum albumin in one volume, with more than 2000 references

Biochemistry

Author: David E. Metzler
Publisher: Academic Press
ISBN: 9780124925403
Format: PDF, Docs
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Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. It also features: thousands of literature references that provide introduction to current research as well as historical background; twice the number of chapters of the first edition; and each chapter contains boxes of information on topics of general interest. -- Publisher description.

Albumin in Medicine

Author: Masaki Otagiri
Publisher: Springer
ISBN: 9811021163
Format: PDF, ePub, Mobi
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This book presents a comprehensive overview of medical and pharmaceutical applications of human serum albumin (HSA), with updates on structural aspects of albumin from the perspectives of X-ray crystallography and NMR, endogenous and exogenous ligand binding of albumin in various pathological conditions, and genetic variants and their phenotypes. Rapid progress and development of its applications have resulted in outstanding results for which albumin has clearly been proven to be a robust biomaterial. Contributions from leading international experts in this field show how HSA is applied to diagnosis, therapy, drugs, and treatment, with a comprehensive introduction of HSA. This volume will appeal to scientists in pharmaceutical and medical research including pharmaceutical chemists, pharmacokineticists, toxicologists, and biochemists not only in academia but also in industry. Readers can effectively acquire the most recent knowledge of applications of HSA and its impact on human health in a single volume.

Hydrolysis in Drug and Prodrug Metabolism

Author: Bernard Testa
Publisher: John Wiley & Sons
ISBN: 9783906390253
Format: PDF, ePub, Docs
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Many drugs and other xenobiotics (e.g., preservatives, insecticides, and plastifiers) contain hydrolyzable moieties such as ester or amide groups. In biological media, such foreign compounds are, therefore, important substrates for hydrolytic reactions catalyzed by hydrolases or proceeding non-enzymatically. Despite their significance, until now, no book has been dedicated to hydrolysis and hydrolases in the metabolism of drugs and other xenobiotics. This work fills a gap in the literature and reviews metabolic reactions of hydrolysis and hydarion from the point of views of enzymes, substrates, and reactions.

Anticholinesterase Pesticides

Author: Tetsuo Satoh
Publisher: John Wiley & Sons
ISBN: 9780470640494
Format: PDF
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This book offers an important reference source about the most common classes of pesticides for researchers engaged in the area of neurotoxicology, metabolism, and epidemiology. The book presents details about thorough characterization of target and non-target enzymes and proteins involved in toxicity and metabolism; and epidemiology of poisonings and fatalities in people from short- and long- term exposures to these pesticides in different occupational settings on an individual country basis as well as on a global basis. The early portion of the book deals with metabolism, mechanisms and biomonitoring of anticholinesterase pesticides, while the later part deals with epidemiological studies, regulatory issues, and therapeutic intervention.

Thiol Redox Transitions in Cell Signaling Part A

Author:
Publisher: Academic Press
ISBN: 9780123813466
Format: PDF, Mobi
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Thiol Redox Transitions in Cell Signaling, Part A, along with its companion (volume 475), presents methods and protocols dealing with thiol oxidation-reduction reactions and their implications as they relate to cell signaling. This first installment of Cadenas and Packer's two-volume treatment specifically deals with glutathionylation and dethiolation, and peroxide removal by peroxiredoxins/thioredoxins and glutathione peroxidases. The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Over 450 volumes have been published to date, and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Along with companion volume, provides a full overview of techniques necessary to the study of thiol redox in relation to cell signaling Gathers tried and tested techniques from global labs, offering both new and tried-and-true methods Relevant background and reference information given for procedures can be used as a guide to developing protocols in a number of disciplines

Thiol Redox Transitions in Cell Signaling

Author:
Publisher: Academic Press
ISBN: 9780123810045
Format: PDF, Kindle
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This volume, along with its companion (volume 474), presents methods and protocols dealing with thiol oxidation-reduction reactions and their implications as they relate to cell signaling. The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Over 450 volumes have been published to date, and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Along with companion volume, provides a full overview of techniques necessary to the study of thiol redox in relation to cell signaling Gathers tried and tested techniques from global labs, offering both new and tried-and-true methods Relevant background and reference information given for procedures can be used as a guide to developing protocols in a number of disciplines

Albumin Structure Function and Uses

Author: Victor M. Rosenoer
Publisher: Elsevier
ISBN: 1483156885
Format: PDF
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Albumin Structure, Function and Uses reviews the many facets of serum albumin, including its history and evolutionary development, structure and function, synthesis, degradation, distribution and transport, and metabolic behavior. The use, misuse, and abuse of albumin in the treatment of disease are also discussed. This book is comprised of 17 chapters and begins with a commentary on how albumin is used, misused, and abused in the treatment of disease such as peptic ulcer, and a description of the real indications for its use. Concepts in albumin purification are then examined, along with the amino acid sequence of serum albumin and some aspects of its structure and conformational properties. Subsequent chapters explore the phylogenetics of albumin; albumin binding sites; clinical implications of drug-albumin interaction; genetics of human serum albumin; and hepatic synthesis of export proteins. Albumin catabolism and intracellular transport are also considered, together with surgical and clinical aspects of albumin metabolism. This monograph should be a useful resource for biochemists and clinicians.

Fluorescence Spectroscopy Imaging and Probes

Author: Ruud Kraayenhof
Publisher: Springer Science & Business Media
ISBN: 3642560679
Format: PDF, ePub
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The increased use of fluorescence techniques is greatly enhanced by the improved instrumentation pioneered by inventive scientists and now made available commercially by several high-tech companies. Moreover, the design and development of many new molecular probes with higher selectivity for specific microenvironmental properties has stimulated many new researchers to employ fluorescence techniques for solving their problems. This topic book, the second in his series, reflects this exciting scientific progress and deals, among others, with new approaches and new probes in fluorescence spectroscopy, single molecule fluorescence, applications in biomembrane and enzyme studies and imaging of living cells.

Principles of Medical Biochemistry E Book

Author: Gerhard Meisenberg
Publisher: Elsevier Health Sciences
ISBN: 032308107X
Format: PDF, ePub
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Principles of Medical Biochemistry condenses the information you need into a comprehensive, focused, clinically-oriented textbook. Drs. Gerhard Meisenberg and William H. Simmons covers the latest developments in the field, including genome research, the molecular basis of genetic diseases, techniques of DNA sequencing and molecular diagnosis, and more. An updated and expanded collection of figures and access to USMLE test questions, clinical case studies, more online at www.studentconsult.com make this the ideal resource for understanding all aspects of biochemistry needed in medicine. Access the complete contents online at www.studentconsult.com, with downloadable illustrations, 150 USMLE-style test questions, 20 clinical case studies, chapter summaries, and integration links to related subjects. Understand biochemistry, cell biology, and genetics together in context through an integrated approach. Get only the information you need for your course with comprehensive yet focused coverage of relevant topics. Review and reinforce your learning using the glossary of technical terms, highlighted in the text and with interactive features online. Tap into the most up-to-date coverage of new developments in genome research, the molecular basis of genetic diseases, techniques of DNA sequencing and molecular diagnosis, RNA interference as a mechanism both for regulation of gene expression and for anti-viral defense, and more. Gain a clear visual understanding through new and updated figures that provide current and relevant guidance. Make the link between basic science and clinical medicine with new Clinical Example boxes in nearly every chapter.