Principles of Chemistry

Author: Nivaldo J. Tro
Publisher: Pearson
ISBN: 0133926222
Format: PDF, ePub
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NOTE: You are purchasing a standalone product; MasteringA&P does not come packaged with this content. If you would like to purchase both the physical text and MasteringA&P search for ISBN-10: 0321971167/ISBN-13: 9780321971166. That package includes ISBN-10: 0321971949/ISBN-13: 9 9780321971944 and ISBN-10: 0133890686/ISBN-13: 9780133890686. A relevant, problem-solving approach to chemistry The Third Edition of Principles of Chemistry: A Molecular Approach presents core concepts without sacrificing rigor, enabling students to make connections between chemistry and their lives or intended careers. Drawing upon his classroom experience as an award-winning educator, Professor Tro extends chemistry to the student’s world by capturing student attention with examples of everyday processes and a captivating writing style. Throughout this student-friendly text, chemistry is presented visually through multi-level images that help students see the connections between the world around them (macroscopic), the atoms and molecules that compose the world (molecular), and the formulas they write down on paper (symbolic). The Third Edition improves upon the hallmark features of the text and adds new assets—Self Assessment Quizzes, Interactive Worked Examples, and Key Concept Videos—creating the best learning resource available for general chemistry students. Also Available with MasteringChemistry This title is also available with MasteringChemistry – an online homework, tutorial, and assessment program designed to work with this text to engage students and improve results. Within its structured environment, students practice what they learn, test their understanding, and pursue a personalized study plan that helps them better absorb course material and understand difficult concepts. Students, if interested in purchasing this title with MasteringChemistry, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information.

The Organic Chemistry of Drug Design and Drug Action

Author: Richard B. Silverman
Publisher: Academic Press
ISBN: 0123820316
Format: PDF, Docs
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The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage. This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries. Updates to all chapters, including new examples and references Chapter 1 (Introduction): Completely rewritten and expanded as an overview of topics discussed in detail throughout the book Chapter 2 (Lead Discovery and Lead Modification): Sections on sources of compounds for screening including library collections, virtual screening, and computational methods, as well as hit-to-lead and scaffold hopping; expanded sections on sources of lead compounds, fragment-based lead discovery, and molecular graphics; and deemphasized solid-phase synthesis and combinatorial chemistry Chapter 3 (Receptors): Drug-receptor interactions, cation-π and halogen bonding; atropisomers; case history of the insomnia drug suvorexant Chapter 4 (Enzymes): Expanded sections on enzyme catalysis in drug discovery and enzyme synthesis Chapter 5 (Enzyme Inhibition and Inactivation): New case histories: for competitive inhibition, the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib and Abelson kinase inhibitor, imatinib for transition state analogue inhibition, the purine nucleoside phosphorylase inhibitors, forodesine and DADMe-ImmH, as well as the mechanism of the multisubstrate analog inhibitor isoniazid for slow, tight-binding inhibition, the dipeptidyl peptidase-4 inhibitor, saxagliptin Chapter 7 (Drug Resistance and Drug Synergism): This new chapter includes topics taken from two chapters in the previous edition, with many new examples Chapter 8 (Drug Metabolism): Discussions of toxicophores and reactive metabolites Chapter 9 (Prodrugs and Drug Delivery Systems): Discussion of antibody–drug conjugates

Chemistry Principles and Practice

Author: Daniel L. Reger
Publisher: Cengage Learning
ISBN: 1111779740
Format: PDF, ePub
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A text that truly embodies its name, CHEMISTRY: PRINCIPLES AND PRACTICE connects the chemistry students learn in the classroom (principles) with real-world uses of chemistry (practice). The authors accomplish this by starting each chapter with an application drawn from a chemical field of interest and revisiting that application throughout the chapter. The Case Studies, Practice of Chemistry essays, and Ethics in Chemistry questions reinforce the connection of chemistry topics to areas such as forensics, organic chemistry, biochemistry, and industry. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.

The Practice of Medicinal Chemistry

Author: Camille Georges Wermuth
Publisher: Elsevier
ISBN: 012417213X
Format: PDF, ePub, Mobi
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The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery. With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research An image bank is available for instructors at www.textbooks.elsevier.com

Introductory Chemistry

Author: Nivaldo J. Tro
Publisher:
ISBN: 9780134302386
Format: PDF
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For one-semester courses in Preparatory Chemistry Builds 21st century and problem solving skills, preparing students for success Now in its 6th Edition, the best-selling Introductory Chemistry continues to encourage student interest by showing how chemistry manifests in students'' daily lives. Author Nivaldo Tro draws upon his classroom experience as an award-winning instructor to extend chemistry from the laboratory to the student''s world, capturing student attention with relevant applications and an engaging writing style. The text provides a superior teaching and learning experience, enabling deep conceptual understanding, fostering the development of problem-solving skills, and encouraging interest in chemistry with concrete examples. Extending chemistry from the lab to the student''s world, the text reveals that anyone can master chemistry. Refined to meet its purpose of teaching relevant skills, the 6th Edition includes new questions, data, and sections to help students build the 21st century skills necessary to succeed in introductory chemistry and beyond. Already a visual text, in this edition the art has been further refined and improved, making the visual impact sharper and more targeted to student learning. The new edition also includes new Conceptual Checkpoints, a widely embraced feature that emphasizes understanding rather than calculation, as well as a new category of end-of-chapter questions called Data Interpretation and Analysis, which present real data in real life situations and ask students to analyze and interpret that data. Also available with Mastering Chemistry. Mastering(tm) Chemistry from Pearson is the leading online homework, tutorial, and assessment system, designed to improve results by engaging students with powerful content. Instructors ensure students arrive ready to learn by assigning educationally effective content and encourage critical thinking and retention with in-class resources such as Learning Catalytics(tm). Students can further master concepts through homework assignments that provide hints and answer-specific feedback. The Mastering gradebook records scores for all automatically graded assignments in one place, while diagnostic tools give instructors access to rich data to assess student understanding and misconceptions. Note: You are purchasing a standalone product; Mastering(tm) Chemistry does not come packaged with this content. Students, if interested in purchasing this title with Mastering Chemistry, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information. If you would like to purchase both the physical text and Mastering Chemistry, search for: 013429081X / 9780134290812 Introductory Chemistry Plus Mastering Chemistry with eText -- Access Card Package, 6/e Package consists of: 0134302389 / 9780134302386 Introductory Chemistry 0134412753 / 9780134412757 Mastering Chemistry with Pearson eText -- ValuePack Access Card -- for Introductory Chemistry Students can use the URL and phone number below to help answer their questions: http://247pearsoned.custhelp.com/app/home 800-677-6337

Principles of Medical Biochemistry E Book

Author: Gerhard Meisenberg
Publisher: Elsevier Health Sciences
ISBN: 0323391907
Format: PDF, Mobi
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For nearly 30 years, Principles of Medical Biochemistry has integrated medical biochemistry with molecular genetics, cell biology, and genetics to provide complete yet concise coverage that links biochemistry with clinical medicine. The 4th Edition of this award-winning text by Drs. Gerhard Meisenberg and William H. Simmons has been fully updated with new clinical examples, expanded coverage of recent changes in the field, and many new case studies online. A highly visual format helps readers retain complex information, and USMLE-style questions (in print and online) assist with exam preparation. Just the right amount of detail on biochemistry, cell biology, and genetics – in one easy-to-digest textbook. Full-color illustrations and tables throughout help students master challenging concepts more easily. Online case studies serve as a self-assessment and review tool before exams. Online access includes nearly 150 USMLE-style questions in addition to the questions that are in the book. Glossary of technical terms. Clinical Boxes and Clinical Content demonstrate the integration of basic sciences and clinical applications, helping readers make connections between the two. New clinical examples have been added throughout the text.

Bacterial Pathogenesis

Author: Virginia L. Clark
Publisher: Gulf Professional Publishing
ISBN: 9780121821371
Format: PDF, ePub, Docs
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This volume of Methods in Enzymology contains contributions covering the wide spectrum of interactions between bacterial pathogens and their eukaryotic hosts. It complements Volume 235, in which methods for the isolation and identification of bacterial pathogens and associated virulence determinants are described. Since the study of bacterial pathogenesis borrows from a great variety of technologies and disciplines, we aim to provide the reader with a representative sample of the most advanced pathogenesis research.